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Difference between revisions of "Epidemiological Parameters"

(Common Questions)
(Common Questions)
Line 33: Line 33:
  
 
  Example 1: The mortality rate μ represents the rate at which individuals die even with no disease.  
 
  Example 1: The mortality rate μ represents the rate at which individuals die even with no disease.  
  For a constant population the mortality rate = the birth rate (or &mu.=&mu.*).   
+
  For a constant population the mortality rate = the birth rate (or μ=μ*).   
 
  For humans, if the average life span is 50 years, and if the time period is 1 day, then  
 
  For humans, if the average life span is 50 years, and if the time period is 1 day, then  
  &mu. = (1/50 years) * (1 year/365.25 days) = (1/18262.5 days)  
+
  μ = (1/50 years) * (1 year/365.25 days) = (1/18262.5 days)  
 
  or
 
  or
  &mu. = 5.476 x 10<sup>-5</sup>[days<sup>-1</sup>].
+
  &mu; = 5.476 x 10<sup>-5</sup>[days<sup>-1</sup>].

Revision as of 15:02, 9 April 2015

STEM TOP BAR.gif

About Epidemiological Parameters

Common Variables and their Units

Using an SEIR model as an example lets discuss some common epidemiological parameters and what they mean. The figure shows the compartments for S=Susceptible, E=Exposed (but not yet infectious), I=Infectious (Shedding Virus), R=Recovered. The arrows show the transitions or people moving between the compartments in a specified time interval. See the page on compartment models.

EpiParams.png

What they mean

The table below shows the epidemiological parameters for the SEIR model shown above. Note that the UNITS or all or the parameters are inverse time.

EpiParamsTable.png Figure 1: SEIR Compartment Model

Each of the parameters are rate constants, but the transmission rate β. has a special role in that it appears inside the mass action term. This interaction term has the product SI.

If the compartments are all normalize so that the total population S+E+I+R = 1
then Susceptible individuals become exposed at a rate, β. SI
For S+E+I+R = P, we have

InterProduct.gif

Common Questions

All of the parameters defined above (and as used in STEM) are rate constants so their values depend on the user specified time period.

Example 1: The mortality rate μ represents the rate at which individuals die even with no disease. 
For a constant population the mortality rate = the birth rate (or μ=μ*).  
For humans, if the average life span is 50 years, and if the time period is 1 day, then 
μ = (1/50 years) * (1 year/365.25 days) = (1/18262.5 days) 
or
μ = 5.476 x 10-5[days-1].

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